Take Back Financial Control: Halfpricesoft.com's ezAccounting Offers In-House Security and Zero Monthly Fees
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As Cloud Subscriptions Drive Up Operating Costs, Small Businesses Turn to Desktop-Based Accounting for Uncompromising Privacy, and Offline Reliability

REDMOND, Wash., Sept. 8, 2026 /PRNewswire/ -- As accounting platforms shift toward forced monthly subscriptions and remote server storage, small business owners, contractors, and bookkeepers are increasingly squeezed by escalating overhead costs and data privacy concerns. Responding to the growing demand for local financial control, Halfpricesoft.com has updated its flagship ezAccounting payroll and business task software, giving small businesses an in-house, desktop-based alternative designed for total data sovereignty, offline operational continuity, and zero recurring monthly fees.

Small business owners looking to step off the SaaS subscription wheel can test the software with a fully functional 30-day trial. Start now!

"Software should serve the business, not tie it to an endless monthly subscription," said Dr. Ge, Founder of Halfpricesoft.com. "As small business owners face subscription fatigue and rising privacy concerns, ezAccounting puts control back where it belongs, in-house. Clients own the data, control the software, and never have to worry about an internet outage stopping payroll or check printing."

Built explicitly for independent contractors, accountants, and growing small businesses, key features of ezAccounting include:

- Complete Data Ownership & Privacy: Financial data remains securely stored on local hard drives, no mandatory cloud sync or remote servers required.

- 100% Offline Functionality: Process invoices, balance general ledgers, and manage payroll without relying on an active internet connection.

- Predictable One-Time Pricing: Eliminate monthly user fees and seat penalties. Single-user licenses start at a flat rate, with optional affordable multi-user upgrades for local network sharing.

- Integrated In-House Check & Paycheck Printing: Print custom MICR-encoded checks on blank stock, process employee paychecks with stubs, and eliminate expensive pre-printed check inventory.

- All-In-One Financial Management: Manage Accounts Payable, Accounts Receivable, customer invoicing, vendor bills, and comprehensive financial reports (Profit & Loss, Balance Sheet, Cash Flow) from a unified dashboard.

- Full Payroll & Tax Compliance: Built-in tax tables for federal and all 50 states, plus capability for printing or direct e-filing of forms 940, 941, W-2, and W-3.

- Securely and easily efile 941/940/94x forms directly through ezPaycheck and ezAccounting using our IRS Authorized system. (Add on fee for this service)

- Unlimited Business Entities: Manage multiple company accounts and employees under one software installation at no extra charge.

Reclaim financial autonomy today. ezAccounting starts at $199.00 for a single installation (per calendar year). The single installation supports unlimited checks for multiple companies for one flat rate. We also offer network versions for a discount prices! Download the risk-free, 30-day trial, no credit card required, by visiting Halfpricesoft.com

About Halfpricesoft.com

Halfpricesoft.com is a trusted provider of affordable small business software, specializing in desktop payroll, accounting, and tax filing solutions. Trusted by tens of thousands of businesses for over 20 years, Halfpricesoft.com focuses on delivering straightforward, easy-to-use software that simplifies administrative tasks without recurring subscription fees. Their product ecosystem includes ezAccounting, ezCheckPrinting, ezPaycheck, ezW2, and ez1099.

SOURCE Halfpricesoft.com

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<p>As Cloud Subscriptions Drive Up Operating Costs, Small Businesses Turn to Desktop-Based Accounting for Uncompromising Privacy, and Offline Reliability REDMOND, Wash., Sept. 8, 2026 /PRNewswire/ -- As accounting platforms shift toward forced monthly subscriptions and remote server storage,...</p>

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Morrisons Partners with Instaleap to Enhance Online Order Fulfilment
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Instaleap technology enables Morrisons to streamline marketplace orders and in-store fulfilment, creating a faster, more convenient experience for customers

New partnership expands Morrisons' relationship with Instacart to create more seamless shopping experiences online and in store

BARCELONA, Spain and BRADFORD, England, Sept. 8, 2026 /PRNewswire/ -- Instaleap, a technology company that provides software for e‑commerce fulfillment and last‑mile operations and is now part of Instacart, and Morrisons today announced a strategic partnership to strengthen Morrisons' ecommerce capabilities and create a faster, more convenient online ordering experience for customers. Through the partnership, Morrisons is now using Instaleap's technology to manage orders across its marketplace channels and help store colleagues fulfil those orders faster and more accurately.

Instaleap is enabling Morrisons to manage orders across marketplace channels including Uber Eats, Just Eat and Deliveroo in one place. Instaleap's in-Store picking app will also give Morrisons store colleagues tools to more efficiently manage the picking and fulfilment process. Together, these capabilities will help Morrisons simplify operations for store teams and create a more seamless online ordering experience for customers.

"We're proud to partner with Morrisons, one of the UK's most respected grocery retailers, as they continue to strengthen their omnichannel offering," said Antonio Nunes, Head of Instaleap. "Consumers now increasingly expect ordering from their local supermarket to be as easy as ordering take-away. Meeting that demand at scale - efficiently, reliably - takes technology built specifically for grocery. That's exactly what we're giving Morrisons."

"We're constantly looking for ways to make online grocery shopping easier and more convenient," said Charlotte Exell, Group Online Director at Morrisons. "More of our customers are choosing to shop from us through one of our immediacy partners and they expect an efficient, dependable service every time. Working with Instaleap powers our online operations behind the scenes, helping us deliver fresh groceries directly to our customers' doors quickly and reliably."

The partnership builds on Instaleap's growing presence across nearly 30 countries, where it supports nearly 80 grocery retailers and marketplaces. It also reflects Instacart's broader strategy to expand its enterprise platform globally, which includes a suite of ecommerce, fulfillment, in-store technology, retail media, and AI solutions.

To learn more about Instaleap's retail technology platform and European e-grocery operations, visit https://instaleap.io. To learn more about Morrisons, visit https://www.morrisons.com/.

About Instaleap by Instacart 

Instaleap by Instacart is a global enablement and fulfilment solutions platform that empowers grocery retailers to streamline and scale their online operations. With purpose-built technology designed to address core retailer needs — including marketplace integrations and fulfilment solutions — Instaleap partners with nearly 80 grocery retailers and marketplaces across almost 30 countries in Europe, Latin America, and the Middle East, and has powered more than 100 million transactions. In April 2026, Instaleap was acquired by Instacart (NASDAQ: CART). For more information, visit instaleap.io.

About Morrisons 

Morrisons is one of the United Kingdom's largest supermarket chains, operating around 500 supermarkets and approximately 1,700 Morrisons Daily convenience stores across England, Wales, and Scotland. Founded in 1899 and headquartered in Bradford, Morrisons is known for its vertically integrated model, in-house manufacturing, and fresh food proposition through its Market Street concept. For more information, visit morrisons.com.

SOURCE Instacart

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<p>Instaleap technology enables Morrisons to streamline marketplace orders and in-store fulfilment, creating a faster, more convenient experience for customers New partnership expands Morrisons' relationship with Instacart to create more seamless shopping experiences online and in store...</p>

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Spirox Launches High-Speed TGV Crack Inspection System to Support High-Volume Glass Substrate Inspection
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Spirox Launches High-Speed TGV Crack Inspection System to Support High-Volume Glass Substrate Inspection

HSINCHU, Sept. 8, 2026 /PRNewswire/ -- Spirox (TWSE: 3055), today hosted the Advanced Packaging Technology Forum, bringing together experts from Corning and DNP to share insights on Glass Core, TGV, reliability, and inspection technologies for next-generation AI and HPC applications. Spirox also unveiled its SP7000G High-Speed TGV Crack Inspection System, strengthening its inspection solutions for high-volume Glass Core and TGV manufacturing.

As AI, HPC, and HBM accelerate advanced packaging development, Glass Core and TGV are emerging as key technologies for next-generation packaging. Odessa Petzold of Corning said, "We are pleased to participate in Spirox's forum and exchange insights with industry partners on the latest developments and challenges in Glass Core. Spirox's laser tomography scanning technology represents an innovative approach to non-destructive inspection of glass materials. Its unique optical inspection capabilities can detect defects within glass structures without damaging the material, making it a valuable tool for advanced packaging processes such as TGV, and helping improve processes and accelerate the transition to high-volume manufacturing."

Satoru Kuramochi of DNP noted, "As AI servers continue to drive demand for high-performance, high-density packaging, reliability and failure analysis will become increasingly important as Glass Core technologies move toward high-volume manufacturing. We are pleased to participate in this forum and share our work on improving the reliability of Glass Core substrates for large AI data server packages. Non-destructive inspection technologies for TGV and glass substrates are expected to play an important role in identifying defects and understanding issues that may occur at different stages of the manufacturing process. Continued advances in inspection and analysis technologies will contribute to improving Glass Core reliability and developing a more comprehensive technology ecosystem."

The SP7000G can complete a full-panel scan of a 510 mm × 515 mm glass substrate in less than 20 minutes, enabling efficient detection of internal microcracks after metallization and ABF build-up processes. It helps improve inspection efficiency, monitor process quality and defect distribution, and optimize yield.

Paul Yang of Spirox Corporation explained, "TGV is moving toward high-volume manufacturing, making inspection efficiency and quality control critical to production. Designed for high-volume manufacturing, the SP7000G complements Spirox's SP8000G, providing a comprehensive solution for high-speed, precise, and non-destructive TGV inspection and analysis across R&D, quality control, and high-volume manufacturing. Spirox will continue to strengthen its proprietary inspection technologies and support customers in accelerating high-volume manufacturing of next-generation packaging technologies."

SOURCE Spirox Corporation

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<p>HSINCHU, Sept. 8, 2026 /PRNewswire/ -- Spirox (TWSE: 3055), today hosted the Advanced Packaging Technology Forum, bringing together experts from Corning and DNP to share insights on Glass Core, TGV, reliability, and inspection technologies for next-generation AI and HPC applications....</p>

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Eliza Appoints Lori Borg as Chief Operating Officer
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SAN FRANCISCO, Sept. 8, 2026 /PRNewswire/ -- Eliza, an AI-native consulting firm that embeds forward-deployed engineers into enterprises to build production AI systems and AI fluency, today announced that Lori Borg has joined as Chief Operating Officer.

Borg will oversee Eliza's operations as the company expands its work with OpenAI and helps more enterprises adopt and build production AI systems.

"Lori brings founder experience, operating discipline, and a deep understanding of partner-driven growth," said Stephen Garden, Co-Founder and CEO of Eliza. "She knows how to build the systems and teams that allow a company to scale without slowing it down. That experience will be critical as we expand our work with OpenAI and help more enterprises move AI into production."

Borg brings more than two decades of experience building and scaling technology businesses across the Microsoft ecosystem. She founded and served as CEO of Northwest Cadence, a Microsoft partner focused on DevOps, software development, data, and AI. The company was acquired by 10th Magnitude in 2018, which was later acquired by Cognizant. Borg went on to serve as Cognizant's Global Head of the Microsoft Alliance, lead MCA Connect's Azure, data, and AI business, and most recently serve as Microsoft's Vice President of Go-to-Market for Americas Enterprise Partner Sales.

"I'm thrilled to join Eliza at such an exciting point in its journey," said Borg. "The growth the company has achieved in such a short time is a testament to the strength of its mission, team, and vision. I'm inspired by what Eliza has built so far and excited to help support its continued momentum and next phase of growth."

Eliza was recently named an OpenAI Advanced Partner and is investing in new talent, deeper industry expertise, and global expansion. As COO, Borg will focus on building the operating foundation needed to support that growth while maintaining the speed and quality Eliza's clients expect.

About Eliza

Eliza is an AI-native consulting firm that helps enterprises build and adopt production AI systems on OpenAI. Its embedded teams combine AI strategy, forward-deployed engineering, workflow redesign, and enablement to move from high-value use cases to systems that operate at scale. Eliza works alongside client teams to transfer capability, so they can own and extend what they build. Learn more at eliza.com.

SOURCE Eliza

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<p>SAN FRANCISCO, Sept. 8, 2026 /PRNewswire/ -- Eliza, an AI-native consulting firm that embeds forward-deployed engineers into enterprises to build production AI systems and AI fluency, today announced that Lori Borg has joined as Chief Operating Officer. Borg will oversee Eliza's...</p>

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Cloud Native Computing Foundation Announces Karmada Graduation
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Multi-cluster, multi-cloud Kubernetes orchestration project reaches production maturity as global enterprises scale AI training and inference across hybrid infrastructure

Key Highlights

- Karmada has graduated from the CNCF, recognizing the project's maturity as an open source engine for orchestrating applications across multiple Kubernetes clusters, clouds, and regions without modifying the applications themselves.

- Karmada v1.19 release advances multi-component scheduling for distributed AI training jobs.

- Global enterprises and leading cloud, telecom, and AI platforms, including Bloomberg, Wellhub, Alibaba Cloud, Huawei, and Trip.com, rely on Karmada for hybrid cloud capacity, multi-region resilience, and multi-cluster AI infrastructure.

SHANGHAI, Sept. 8, 2026 /PRNewswire/ -- KubeCon + CloudNativeCon + OpenInfra Summit + PyTorch Conference China 2026 — The Cloud Native Computing Foundation® (CNCF®), which builds sustainable ecosystems for cloud native software, today announces the graduation of Karmada, an open source project that lets organizations run applications across multiple Kubernetes clusters, clouds, and regions without changing the applications themselves.

This milestone comes as Karmada advances multi-cluster AI infrastructure through its v1.19 release, which advances multi-component scheduling for distributed AI training jobs and promotes priority-based scheduling to Beta, enabled by default, to ensure critical workloads are scheduled first. The project's production footprint now powers mission-critical infrastructure for a diverse global adopter base, ranging from global enterprises like Bloomberg and Wellhub to major cloud, telecom, and AI platforms across Asia.

"As organizations scale Kubernetes across clusters and GPU constrained AI environments, having a production ready way to coordinate that fleet becomes critical to operational success," said Chris Aniszczyk, CTO, CNCF. "Reaching CNCF graduation demonstrates that Karmada has achieved the technical maturity, governance, and security work required for the enterprise; we look forward to seeing the project continue to grow within the ecosystem."

Short for Kubernetes Armada, Karmada extends the standard Kubernetes API with centralized placement, propagation, failover, and multi-cluster autoscaling. Karmada's CNCF history dates back to its first commit in November 2020. The project then officially joined in September 2021 as a Sandbox project before advancing to Incubating status in December 2023.

Since joining CNCF, Karmada has grown to more than 1,214 contributors across 292 contributing organizations and more than 5,600 GitHub stars. Its production adopter base includes a significant portion of Chinese cloud, internet, telecom, AI, travel, logistics, device, and enterprise organizations, including Alibaba Cloud, Bilibili, Huawei, iFLYTEK, JDCloud, Kuaishou, RedNote, SenseTime, Trip.com, Vivo, WPS, and ZTO, alongside global adopters like Bloomberg and Wellhub. These companies use Karmada to support hybrid cloud capacity, multi-region resilience, intelligent traffic distribution, AI training, GPU/CPU scheduling, multi-cluster application delivery, and fleet-wide service-configuration distribution.

Karmada also integrates directly with existing CNCF observability and deployment projects: it exports Prometheus metrics across its control-plane components, packages an etcd instance for control-plane state, and ships Helm charts for installation.

"I am proud that Karmada has grown into critical infrastructure that large enterprises count on — powering everything from microservices to big data and AI," said Hongcai Ren, Karmada maintainer. "None of this would have happened without the open, neutral platform CNCF built, where adopters and developers explore this space side by side. Graduation is a new starting point: we look forward to partnering with more adopters, learning from richer real-world scenarios, and working with the broader ecosystem to tackle the challenges of AI and agent infrastructure together."

Karmada's broader 2026 roadmap builds on that foundation, moving multi-cluster Kubernetes from basic workload propagation toward a more resource-aware control plane. It also includes priority-based preemption, multi-cluster queuing for AI training and batch jobs, and multi-cluster support for Kubernetes Dynamic Resource Allocation (DRA) across GPUs and other accelerators.

To reach graduation status, Karmada completed a third-party security audit, established a formal steering committee to ensure transparent governance, and adopted the CNCF Code of Conduct. The project also maintains a Core Infrastructure Initiative (CII) Best Practices Badge, demonstrating a commitment to secure software development.

The CNCF Technical Oversight Committee (TOC) provides technical leadership to the cloud native community, defining its vision and stewarding projects through maturity levels up to graduation.

The announcement was made during KubeCon + CloudNativeCon + OpenInfra Summit + PyTorch Conference China 2026, where these three Foundations convened together in China for the first time on a single stage, underscoring the growing need for multi-cluster orchestration that spans private data centers, public clouds, and specialized AI hardware.

Supporting Quotes

"As organizations scale beyond a single Kubernetes cluster, they need consistent management without added complexity. Karmada solves this by extending familiar Kubernetes APIs to work across clusters and clouds. With maintainers across six organizations and adopters running it at significant scale, we congratulate Karmada on its successful graduation as a CNCF project," – Chad Beaudin, TOC Sponsor.

"Karmada has become foundational to how Bloomberg operates resilient cloud native infrastructure. By automating disaster recovery, improving resource utilization, and simplifying the management of individual Kubernetes clusters, it has enabled our platform engineering teams to operate more efficiently, while also giving internal application teams a simpler, more consistent experience deploying jobs. As close collaborators with the Karmada community over the past few years, we have seen this open source project continue to evolve, and its graduation reflects its growing importance to enterprise organizations that are managing complex Kubernetes environments." – Michas Szacillo, Engineering Team Lead of Bloomberg's Streaming Platform and Karmada maintainer

"At Trip.com, Karmada has become a critical part of our multi-cluster infrastructure and has delivered significant value in production. Without changing existing Kubernetes resource definitions, it has enabled us to operate multiple clusters as a unified resource pool, support cross-cluster elasticity and failover, bring new clusters into production more efficiently, and perform large-scale workload migration with minimal disruption to applications. This has greatly reduced the complexity of operating infrastructure at scale. As computing increasingly spans regions, clouds, and heterogeneous resources, we believe Karmada will become an essential foundation for reliable and scalable cloud-native and AI infrastructure." – Honghui Yue, Senior Development Expert, Trip.com

"Karmada powers multi-cluster orchestration in DaoCloud's enterprise platform, helping customers implement multi-cloud strategies through a consistent, Kubernetes-native experience across clusters and environments. Compatibility with Kubernetes APIs and existing toolchains makes it practical for production, while our community participation turns customer feedback into upstream improvements. We are extending this foundation to our AI Token Factory architecture as multi-cluster inference across data centers becomes increasingly important. Graduation gives us greater confidence in Karmada as a long-term foundation, and we look forward to contributing more capabilities for production AI inference," – Kay Yan, Chief Architect, DaoCloud.

For more information about Karmada, visit https://karmada.io/.

About Cloud Native Computing Foundation

Cloud native computing empowers organizations to build and run scalable applications with an open source software stack in public, private, and hybrid clouds. The Cloud Native Computing Foundation (CNCF) hosts critical components of the global technology infrastructure, including Kubernetes, Prometheus, and Envoy. CNCF brings together the industry's top developers, end users, and vendors and runs the largest open source developer conferences in the world. Supported by nearly 800 members, including the world's largest cloud computing and software companies, as well as over 200 innovative startups, CNCF is part of the nonprofit Linux Foundation. For more information, please visit www.cncf.io.

Media Contact

The Linux Foundation

[email protected]

SOURCE Cloud Native Computing Foundation

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<p>Multi-cluster, multi-cloud Kubernetes orchestration project reaches production maturity as global enterprises scale AI training and inference across hybrid infrastructure Key Highlights Karmada has graduated from the CNCF, recognizing the project's maturity as an open source engine for...</p>

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MEXC Launches "Trade Wall Street Without Walls" to Break Traditional Barriers to Stock Market Participation
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MEXC Launches "Trade Wall Street Without Walls" to Break Traditional Barriers to Stock Market Participation

74.2% of surveyed TradFi users have shifted some or all traditional asset trading activity to crypto exchanges, reflecting growing demand for more flexible market access

MUTSAMUDU, Comoros, Sept. 8, 2026 /PRNewswire/ -- MEXC, a pioneer in 0-fee digital asset trading, today launched "Trade Wall Street, Without Walls." The campaign highlights how crypto-native trading is reducing traditional barriers to stock market participation, including access, fees and limited trading hours. As crypto exchanges expand into traditional assets, retail users are gaining more flexible ways to access and trade global market opportunities.

The campaign comes amid a broader shift in how investors trade traditional financial assets. Recent research from MEXC and CoinGecko found that 74.2% of surveyed users with traditional finance experience had shifted some or all of their traditional asset trading activity to crypto exchanges. Among the biggest frustrations users cited with traditional brokerages were limited trading hours, at 58.8%, and high fees, at 54.7%. In contrast, 24/7 market access and more competitive fees ranked among the leading reasons users chose to move traditional asset trading activity to centralized exchanges.

The findings point to a change that goes beyond simply making more assets available on crypto platforms. Investors are not only looking for more assets. They are also looking for a different way to access and trade them. The always-on, lower-friction trading experience developed in crypto is increasingly influencing expectations across a broader financial landscape, particularly as users move more easily between crypto, stocks, commodities, tokenized assets and other markets.

"Trade Wall Street, Without Walls." brings this shift to life through five traditional market "walls": the Access Wall, Fee Wall, Time Wall, Capital Wall and Direction Wall. Together, they represent common constraints that have historically shaped retail participation in stock markets, from where and when users can trade to the costs, capital requirements and trading strategies available to them. The campaign highlights how crypto-native market infrastructure is beginning to reduce these frictions and create more flexible ways for retail users to participate in traditional financial opportunities.

On MEXC, this evolution is reflected in a growing range of stock-related products and participation models across different stages of the market. The MEXC Stock Ecosystem spans the full market lifecycle, from Pre-IPO to IPO and Post-IPO, including Pre-IPO Futures and Pre-IPO Launchpad for the Pre-IPO stage, IPO Launchpad and IPO Express for the IPO stage, and RealStocks, Tokenized Stocks, and Stock Futures for Post-IPO markets. Bringing private-market themes, public equities and derivatives into a more integrated trading environment. Selected products also offer features such as 0-fee trading, USDT-based participation, extended or around-the-clock market access, and the ability to take both long and short positions, giving users more flexibility in how they respond to different market conditions. Product availability and trading conditions may vary by region and product.

"The biggest change is not simply that more traditional assets are becoming available on crypto platforms. It is that the way retail users access and trade those assets is changing," said Vugar Usi Zade, CEO of MEXC. "For decades, traditional markets have been shaped by boundaries around access, time, cost, capital and direction. Crypto-native infrastructure gives us an opportunity to rethink many of those constraints and build a market experience that is more open, flexible and responsive to the needs of retail users."

The shift also reflects a broader convergence between crypto and traditional finance. As centralized exchanges evolve from crypto-only trading venues into broader multi-asset platforms, the distinction between where users trade crypto and where they access traditional assets is becoming less rigid. For retail investors, this means the value of a platform is increasingly defined not only by the number of assets it offers, but also by how easily users can move across different markets, respond to opportunities and manage capital within a single trading environment.

At the same time, reducing structural barriers is only one part of broader market participation. As crypto-native users gain access to more stocks and traditional financial products, the ability to understand different markets, evaluate opportunities and assess risk becomes increasingly important. Alongside "Trade Wall Street, Without Walls.", MEXC is also introducing Opportunity Compass, a global markets education initiative designed to help users build a more systematic understanding of asset classes, market drivers, emerging financial models and risk in an increasingly multi-asset environment.

About MEXC

Founded in 2018, MEXC is a leading global multi-asset trading platform built as your 0-fee gateway to infinite opportunities. Serving users across 170+ markets, MEXC provides simple and efficient access to crypto, stocks, tokenized assets, derivatives, and a growing range of TradFi-linked opportunities through one account and one gateway.

With 0 trading fees, deep liquidity, broad asset coverage, and a high-performance trading experience, MEXC is designed for retail users who want to discover earlier, act faster, and trade with fewer barriers. As crypto and traditional finance continue to converge, MEXC is committed to making global opportunities more accessible, helping users trade freely and MEXCmize every opportunity.

MEXC Official Website| X | Telegram |How to Sign Up on MEXC

SOURCE MEXC

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<p>74.2% of surveyed TradFi users have shifted some or all traditional asset trading activity to crypto exchanges, reflecting growing demand for more flexible market access MUTSAMUDU, Comoros, Sept. 8, 2026 /PRNewswire/ -- MEXC, a pioneer in 0-fee digital asset trading, today launched "Trade...</p>

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PeproMene Bio Announces Publication in The Lancet of Breakthrough Phase 1 Clinical Trial Results Demonstrating Deep and Durable Complete Responses in Relapsed/Refractory B-cell Lymphomas, including after prior CD19 CAR T-cell failure
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PeproMene Bio Announces Publication in The Lancet of Breakthrough Phase 1 Clinical Trial Results Demonstrating Deep and Durable Complete Responses in Relapsed/Refractory B-cell Lymphomas, including after prior CD19 CAR T-cell failure

News provided by

PeproMene Bio, Inc.; Institute for Follicular Lymphoma Innovation (IFLI)

Sep 08, 2026, 06:01 ET

IRVINE, Calif., Sept. 8, 2026 /PRNewswire/ -- PeproMene Bio, Inc. today announced the publication in The Lancet, one of the world's leading medical journals, of results from its Phase 1 clinical trial evaluating PMB-CT01, the company's first-in-class BAFF-R-targeted CAR T-cell therapy, in patients with relapsed or refractory B-cell non-Hodgkin lymphoma.

The publication reports durable complete clinical responses, together with a more favorable safety profile compared with approved CAR T-cell therapies. Seven of nine treated patients (80%) achieved a complete response (CR), including four of six patients who had progressed after conventional CD19-directed CAR T-cell therapy ("CAR after CAR"). All complete responses remained ongoing at the time of data cutoff, with no relapses observed and the longest ongoing complete response reaching 35 months, suggesting the likelihood of cure.

PMB-CT01 was remarkably safe, as all cytokine release syndrome (CRS) events and the two reported immune effector cell-associated neurotoxicity syndrome (ICANS) events were limited to Grade 1.

Based on these promising results, the Phase 1 trial has expanded from a single clinical trial site at City of Hope, a cancer research and treatment organization, to multiple additional medical centers across the United States. The publication also reports that the first patient treated in the expansion phase—who had triple-hit high-grade B-cell lymphoma following progression after CD19-directed CAR T-cell therapy—also achieved a complete response at the first disease assessment.

"Publishing these peer-reviewed data in The Lancet represents a significant recognition of this novel therapy," said Larry W. Kwak, M.D., Ph.D., scientific founder of PeproMene Bio. "With the lack of any relapses, we believe PMB-CT01 is a paradigm-shifting CAR T-cell option for blood cancers which were previously thought to be incurable. Its elite safety may also enable outpatient administration—improving access for underserved patients—while also opening doors for treating autoimmune diseases where B-cell depletion is already proven."

"These early results are encouraging, particularly for patients whose disease progressed after CD19 or CD20-directed T-cell therapy," said Stephen Forman, M.D., paper co-author and director of the Hematologic Malignancies Institute at City of Hope. "City of Hope will continue to support the trial as the coordinating center and manufacturing site in addition to patient enrollment."

In December 2024, the Institute for Follicular Lymphoma Innovation (IFLI) committed up to $11 million to support the clinical development of PMB-CT01 in patients with relapsed or refractory follicular lymphoma. "For patients whose lymphoma returns after CD19-directed CAR T-cell therapy, a new target can mean a new chance. IFLI is proud to support PeproMene Bio in advancing BAFF-R CAR T-cell therapy and encouraged by these early, durable responses," said Mehrdad Mobasher, M.D., M.P.H., Executive Partner at the Institute for Follicular Lymphoma Innovation.

Publication Details

Title: BAFF-R CAR T-cell therapy for relapsed or refractory B-cell lymphomas

Journal: The Lancet (Research Letter)

DOI: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01329-2/fulltext

About PMB-CT01

PMB-CT01 is a first-in-class B-cell activating factor receptor (BAFF-R)-targeted autologous CAR T-cell therapy being evaluated in ongoing Phase 1 trials for relapsed/refractory B-NHL and relapsed/refractory B-ALL. BAFF-R is expressed almost exclusively on B cells and is essential for B-cell survival, reducing the likelihood of antigen-loss escape. PeproMene Bio has licensed intellectual property relating to PMB-CT01 from City of Hope.

About PeproMene Bio

PeproMene Bio, Inc. is a clinical-stage biotech company in Irvine, California developing novel therapies to treat cancers and immune disorders. For more information, contact Hazel Cheng, Ph.D., COO of PeproMene Bio, Inc. at [email protected] or visit https://pepromenebio.com/.

Forward-Looking Statements

This press release contains forward-looking statements subject to risks and uncertainties, including risks related to clinical development, regulatory outcomes, therapeutic potential, and commercialization. PeproMene Bio undertakes no obligation to update forward-looking statements except as required by law.

Media Contact, IFLI

Laura DiCaprio, APR

McDougall Communications

[email protected]

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QA FAIL (need review): TARGET claims the trial specifically enrolled patients who had progressed after CD19-directed CAR T-cell therapy, but SOURCE states the trial enrolled relapsed/refractory B-cell non-Hodgkin lymphoma patients broadly, with only a subgroup having had prior CD19 CAR T therapy. This unsupported patient-population claim is a material factual inaccuracy.
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<p>IRVINE, Calif., Sept. 8, 2026 /PRNewswire/ -- PeproMene Bio, Inc. today announced the publication in The Lancet, one of the world's leading medical journals, of results from its Phase 1 clinical trial evaluating PMB-CT01, the company's first-in-class BAFF-R-targeted CAR T-cell therapy, in...</p>

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RXT Lawsuit Alert: Rackspace Technology Investors Face September 28 Deadline After 33% Stock Drop Tied to AI Effort Issues
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A securities fraud class action lawsuit has been filed on behalf of Rackspace investors after its stock plummeted 33.6% because Rackspace allegedly misled investors about its AI efforts and their impact on the company's financial performance.

NEW YORK, Sept. 8, 2026 /PRNewswire/ -- Leading securities law firm Bleichmar Fonti & Auld LLP announces that a class action lawsuit has been filed against Rackspace Technology, Inc. (NASDAQ:RXT) and certain of the company's senior executives for securities fraud after its significant stock drop resulting from potential violations of the federal securities laws.

If you invested in Rackspace, you are encouraged to obtain additional information by visiting: https://www.bfalaw.com/cases/rackspace-class-action-lawsuit.

Key Details of the Rackspace ($RXT) Class Action:

- Lead Plaintiff Deadline: September 28, 2026

- Alleged Misconduct: Securities fraud alleging that Rackspace misled investors about its AI efforts and their impact on the company's financial performance

- Stock Drop: July 9, 2026 – 33.6% Stock Drop

- Court: U.S. District Court for the Southern District of New York

- Action: Contact BFA Law to discuss your rights

Investors have until September 28, 2026 to ask the Court to be appointed to lead the case. The complaint asserts securities fraud claims under Sections 10(b) and 20(a) of the Securities Exchange Act of 1934 on behalf of investors in Rackspace securities. The class action is pending in the U.S. District Court for the Southern District of New York. It is captioned Morgan-Reed v. Rackspace Technology, Inc., No. 26-cv-6491.

Why is Rackspace Being Sued for Securities Fraud?

Rackspace is a hybrid cloud and AI solutions company that operates physical infrastructure to host cloud services and artificial intelligence. The company also provides Rackspace AI, a portfolio of AI services to help organizations scale AI adoption.

During the relevant period, the company announced it signed a memorandum of understanding with Advanced Micro Devices, Inc. ("AMD") to assist in building out its AI infrastructure and enhance its AI capabilities. That same day, the company reaffirmed its full year revenue guidance.

Rackspace told investors that the "AMD piece really fits into how" the company's technology stack operates. Rackspace also stated that the AMD partnership "give[s] [the Company] confidence in the full year Private Cloud growth profile."

As alleged, in truth, the company's AI efforts would require Rackspace to significantly re-prioritize its capacity and pull capacity away from revenue generating segments.

Why did Rackspace's Stock Drop?

On July 9, 2026, Rackspace revealed that its AI investments would require a significant re-prioritization of resources and a "transition away" from certain revenue generating segments. As a result, Rackspace revealed it was cutting its full year 2026 revenue guidance by $150 million and its full year Private Cloud revenue outlook by $25 million.

This news caused the price of Rackspace stock to decline $2.21 per share, or 33.6%, from a closing price of $6.58 per share on July 8, 2026, to $4.37 per share on July 9, 2026.

Click here for more information: https://www.bfalaw.com/cases/rackspace-class-action-lawsuit.

What Can You Do?

If you invested in Rackspace, you may have legal options and are encouraged to submit your information to the firm.

All representation is on a contingency fee basis; there is no cost to you. Shareholders are not responsible for any court costs or expenses of litigation. The firm will seek court approval for any potential fees and expenses.

Submit your information by visiting:

https://www.bfalaw.com/cases/rackspace-class-action-lawsuit

Why Bleichmar Fonti & Auld LLP?

BFA is a leading international law firm representing plaintiffs in securities class actions and shareholder litigation. It has been named a top plaintiff law firm by Chambers USA, The Legal 500, and ISS SCAS, and its attorneys have been named "Elite Trial Lawyers" by the National Law Journal, "Litigation Stars" by Benchmark Litigation, among the top "500 Leading Plaintiff Financial Lawyers" by Lawdragon, "Titans of the Plaintiffs' Bar" by Law360 and "SuperLawyers" by Thomson Reuters.

Most recently, The Legal 500 awarded BFA the most client satisfaction accolades of any plaintiff's securities litigation law firm, with clients noting: "[t]here is no better service provider in the practice area," "[t]he interest of the client is always front and center," and "[t]here isn't a better firm in this space." One testimonial described the firm as "nimble and entrepreneurial," with a "relentless focus on adding value for clients."

Among its recent notable successes, BFA recovered over $900 million in value from Tesla, Inc.'s Board of Directors, as well as $420 million from Teva Pharmaceutical Ind. Ltd.

For more information about BFA and its attorneys, please visit https://www.bfalaw.com.

https://www.bfalaw.com/cases/rackspace-class-action-lawsuit

Attorney advertising. Past results do not guarantee future outcomes.

SOURCE Bleichmar Fonti & Auld LLP

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<p>A securities fraud class action lawsuit has been filed on behalf of Rackspace investors after its stock plummeted 33.6% because Rackspace allegedly misled investors about its AI efforts and their impact on the company's financial performance. NEW YORK, Sept. 8, 2026 /PRNewswire/ --...</p>

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CDNL Investigation Alert: Cardinal Infrastructure Faces Securities Fraud Investigation After 36% Stock Drop Tied to Acquisition Issues
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BFA Law is investigating whether Cardinal Infrastructure Group, Inc. committed securities fraud relating to statements about the performance of the A.L. Grading Contractors acquisition.

NEW YORK, Sept. 8, 2026 /PRNewswire/ -- Leading securities law firm Bleichmar Fonti & Auld LLP announces an investigation into Cardinal Infrastructure Group, Inc. (NASDAQ:CDNL) for potential securities fraud after its significant stock drop.

If you invested in Cardinal Infrastructure securities, you are encouraged to obtain additional information by visiting: https://www.bfalaw.com/cases/cardinal-infrastructure-class-action-lawsuit.

Key Details of the Cardinal Infrastructure Group ($CDNL) Class Action Investigation:

- Investigation Overview: Securities fraud relating to Cardinal's statements about the performance of the A.L. Grading Contractors acquisition.

- Stock Decline: August 11, 2026 – 36% Stock Drop

- Action: Contact BFA Law to discuss your rights

Why is Cardinal Infrastructure Being Investigated for Securities Fraud?

Cardinal Infrastructure is a heavy construction infrastructure services company that went public in December 2025 and has grown through acquisitions.

BFA is investigating whether Cardinal misled investors about the performance of one of its acquired businesses named A.L. Grading Contractors.

Why did Cardinal Infrastructure's Stock Drop? 

On August 11, 2026, Cardinal reported Q2 2026 results. Although revenues increased year over year, the company reported adjusted EBITDA margin of only 12.4%, far below the 20%+ margin it had told investors to expect, due to increased costs and scalability issues at least partially related to A.L. Grading Contractors.

This news caused the price of Cardinal Infrastructure stock to drop $21.73 per share, or over 36%, from a closing price of $60.00 per share on August 10, 2026, to $38.27 per share on August 11, 2026, the following trading day.

Click here for more information: https://www.bfalaw.com/cases/cardinal-infrastructure-class-action-lawsuit.

What Can You Do?

If you invested in Cardinal Infrastructure securities, you may have legal options and are encouraged to submit your information to the firm.

All representation is on a contingency fee basis; there is no cost to you. Shareholders are not responsible for any court costs or expenses of litigation. The firm will seek court approval for any potential fees and expenses.

Submit your information by visiting:

https://www.bfalaw.com/cases/cardinal-infrastructure-class-action-lawsuit

Why Bleichmar Fonti & Auld LLP?

BFA is a leading international law firm representing plaintiffs in securities class actions and shareholder litigation. It has been named a top plaintiff law firm by Chambers USA, The Legal 500, and ISS SCAS, and its attorneys have been named "Elite Trial Lawyers" by the National Law Journal, "Litigation Stars" by Benchmark Litigation, among the top "500 Leading Plaintiff Financial Lawyers" by Lawdragon, "Titans of the Plaintiffs' Bar" by Law360 and "SuperLawyers" by Thomson Reuters.

Most recently, The Legal 500 awarded BFA the most client satisfaction accolades of any plaintiff's securities litigation law firm, with clients noting: "[t]here is no better service provider in the practice area," "[t]he interest of the client is always front and center," and "[t]here isn't a better firm in this space." One testimonial described the firm as "nimble and entrepreneurial," with a "relentless focus on adding value for clients."

Among its recent notable successes, BFA recovered over $900 million in value from Tesla, Inc.'s Board of Directors, as well as $420 million from Teva Pharmaceutical Ind. Ltd.

For more information about BFA and its attorneys, please visit https://www.bfalaw.com.

https://www.bfalaw.com/cases/cardinal-infrastructure-class-action-lawsuit

Attorney advertising. Past results do not guarantee future outcomes.

SOURCE Bleichmar Fonti & Auld LLP

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CDNL Investigation Alert
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<p>BFA Law is investigating whether Cardinal Infrastructure Group, Inc. committed securities fraud relating to statements about the performance of the A.L. Grading Contractors acquisition. NEW YORK, Sept. 8, 2026 /PRNewswire/ -- Leading securities law firm Bleichmar Fonti & Auld LLP...</p>

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DKS Investigation Alert: Dick's Sporting Goods Faces Securities Fraud Investigation After 30% Stock Drop Tied to Inventory Issues
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BFA Law is investigating whether Dick's Sporting Goods, Inc. committed securities fraud relating to statements about the Foot Locker acquisition and related inventory, discounting, and profit pressures.

NEW YORK, Sept. 8, 2026 /PRNewswire/ -- Leading securities law firm Bleichmar Fonti & Auld LLP announces an investigation into Dick's Sporting Goods, Inc. (NYSE:DKS) for potential securities fraud after its significant stock drop.

If you invested in Dick's Sporting Goods securities, you are encouraged to obtain additional information by visiting: https://www.bfalaw.com/cases/dick-sporting-class-action-lawsuit.

Key Details of the Dick's Sporting Goods ($DKS) Class Action Investigation:

- Investigation Overview: Securities fraud relating to Dick's statements about the Foot Locker acquisition and related inventory, discounting, and profit pressures.

- Stock Decline: August 25, 2026 – 30% Stock Drop

- Action: Contact BFA Law to discuss your rights

Why is Dick's Sporting Goods Being Investigated for Securities Fraud?

Dick's Sporting Goods is a sporting goods retailer. It acquired Foot Locker in a $2.4 billion deal that increased its exposure to the sneaker market.

BFA is investigating whether Dick's misled investors about the Foot Locker acquisition, including the risks from excess inventory, weak footwear demand, and heavy promotions by competitors.

Why did Dick's Sporting Goods' Stock Drop? 

On August 24, 2026, Dick's announced lower annual profits, weaker footwear demand, excess sneaker inventory, and heavy discounting needed to keep pace with competitors after the Foot Locker acquisition.

Following that announcement, Dick's Sporting Goods shares fell approximately 30% on August 25, 2026.

Click here for more information: https://www.bfalaw.com/cases/dick-sporting-class-action-lawsuit.

What Can You Do?

If you invested in Dick's Sporting Goods securities, you may have legal options and are encouraged to submit your information to the firm.

All representation is on a contingency fee basis; there is no cost to you. Shareholders are not responsible for any court costs or expenses of litigation. The firm will seek court approval for any potential fees and expenses.

Submit your information by visiting:

https://www.bfalaw.com/cases/dick-sporting-class-action-lawsuit

Why Bleichmar Fonti & Auld LLP?

BFA is a leading international law firm representing plaintiffs in securities class actions and shareholder litigation. It has been named a top plaintiff law firm by Chambers USA, The Legal 500, and ISS SCAS, and its attorneys have been named "Elite Trial Lawyers" by the National Law Journal, "Litigation Stars" by Benchmark Litigation, among the top "500 Leading Plaintiff Financial Lawyers" by Lawdragon, "Titans of the Plaintiffs' Bar" by Law360 and "SuperLawyers" by Thomson Reuters.

Most recently, The Legal 500 awarded BFA the most client satisfaction accolades of any plaintiff's securities litigation law firm, with clients noting: "[t]here is no better service provider in the practice area," "[t]he interest of the client is always front and center," and "[t]here isn't a better firm in this space." One testimonial described the firm as "nimble and entrepreneurial," with a "relentless focus on adding value for clients."

Among its recent notable successes, BFA recovered over $900 million in value from Tesla, Inc.'s Board of Directors, as well as $420 million from Teva Pharmaceutical Ind. Ltd.

For more information about BFA and its attorneys, please visit https://www.bfalaw.com.

https://www.bfalaw.com/cases/dick-sporting-class-action-lawsuit

Attorney advertising. Past results do not guarantee future outcomes.

SOURCE Bleichmar Fonti & Auld LLP

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<p>BFA Law is investigating whether Dick's Sporting Goods, Inc. committed securities fraud relating to statements about the Foot Locker acquisition and related inventory, discounting, and profit pressures. NEW YORK, Sept. 8, 2026 /PRNewswire/ -- Leading securities law firm Bleichmar Fonti &...</p>

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