"As the airline that democratized the skies, Southwest Airlines® has always helped make the dream trip a reality and our new campaign, 'Enter Airplane Mode,' encourages Customers to recognize when they're approaching a breaking point and to turn that moment into their booking point," said Sabrina Callahan, Senior Vice President and Chief Digital & Marketing Officer. "With a Customer extension called 'Notification Vacation' we are taking it one step further from simply encouraging you to take the trip to helping you bring it to fruition."

Notification Vacation offers an opportunity for Customers to set aside the burnout and finally take the trip. With an interactive online activation that converts notifications into Rapid Rewards® points, Customers can upload a screenshot of their homepage notifications and receive Rapid Rewards points.⁶ It is an easy way to turn constant pings into a positive, reminding busy Americans that the reset they need may be closer than they think. Customers can also take a Burnout Quiz⁷ to understand their level of burnout and find inspiration for their next relaxing getaway. Together, Notification Vacation and the Burnout Quiz offer Customers the chance to receive more than 185 million Rapid Rewards points total, with limits applying per Rapid Rewards Member.⁸

The "Enter Airplane Mode" campaign spots were shot by Hollywood directors Will Speck and Josh Gordon and voiced by Adam Scott, whose recent role in a workplace-centered series adds a culturally relevant wink to the message about disconnecting from work and reconnecting with life beyond it. Created with ad agency GSD&M, the campaign begins airing today and brings "Enter Airplane Mode" to life through relatable moments of everyday stressors, from overloaded calendars to endless meetings and packed commutes. Southwest is also working with creator agency, Later, and media agency, Spark Foundry, to bring the campaign to life as part of a full 360-degree effort.

Southwest continues to make getting away easier with purposeful, feedback-driven enhancements—from updated boarding and assigned seating to onboard investments such as free WiFi for Rapid Rewards® Members thanks to T-Mobile®⁹ and Starlink's fastest WiFi in the sky. Together with its flexible policies, expansive domestic network, and Hospitality that defines the brand, Southwest is making it easier for Customers to disconnect and enter airplane mode.

Visit the Southwest Newsroom at swamedia.com for multimedia assets and other Company news.

ABOUT SOUTHWEST AIRLINES CO.

Southwest Airlines Co. operates one of the world's most admired and awarded airlines, offering its one-of-a-kind value and Hospitality at 120 airports across 12 countries. Southwest took flight in 1971 to democratize the sky through friendly, reliable, and low-cost air travel and now carries more air travelers flying nonstop within the United States than any other airline⁴. By empowering its more than 73,000¹⁰ People to deliver unparalleled Hospitality, the maverick airline cherishes a passionate loyalty among more than 134 million Customers carried in 2025. Southwest leverages a unique legacy and mission to serve communities around the world including harnessing the power of its People and Purpose to put communities at the Heart of its success. Learn more by visiting Southwest.com/citizenship.

1. Based on a Southwest-sponsored online survey conducted in August 2026 with 2,000+ adults aged 18-64 in the U.S.

2. Fare difference may apply.

3. Basic fare round trip bookings must be canceled or upgraded. Cancel 10+ minutes before departure to avoid forfeiture of travel funds.

4. Based on U.S. Dept. of Transportation quarterly Airline Origin & Destination Survey as of Q4 2025.

5. Southwest Airlines Co. ranked first in Best Cabin Crew through USA Today's 2025 10 Best.

6. NO PURCHASE NECESSARY. Open to Rapid Rewards® Members; 18+; 50 US/DC. Limit one (1) entry per Member. Minimum award: 1,000 Rapid Rewards points. Maximum award: 10,000 Rapid Rewards points per Member. Total points available: 150,000,000. Points available while supplies last; daily availability may be limited. Points subject to verification. Void where prohibited. See Official Terms and Conditions. 

7. NO PURCHASE NECESSARY. Open to Rapid Rewards® Members; 18+; 50 US/DC. Limit one (1) quiz completion per Member. Each eligible, verified completion receives 500 Rapid Rewards points, subject to availability. Total points available: 37,000,000. Once all points have been awarded, the promotion ends. Points subject to verification; see Terms for eligibility, fraud prevention, and disqualification provisions. Void where prohibited. See Official Terms and Conditions. 

8. 187 million total points represents the combined maximum available across two separate promotions: up to 150 million points through Notification Vacation and up to 37 million points through the Burnout Quiz. Individual awards are capped at 10,000 points for Notification Vacation Promotion and 500 points for Burnout Quiz Promotion. Separate eligibility, entry, award, and point-limit terms apply. Points are available while supplies last, and no individual may receive the combined total. See each promotion's Official Terms and Conditions for full details, including per-Member point caps and entry limits.

9. Where available. Available only on WiFi-enabled designated aircraft.

10. Fulltime-equivalent active Employees as of June 30, 2026.

Visit the Southwest Newsroom at swamedia.com.

SOURCE Southwest Airlines Co.

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New release transforms voice AI from a reactive answering tool into an always-on hospitality team member that remembers regulars, anticipates guest needs, speaks nearly 100 languages, and drives revenue at scale across multiple channels.

NEW YORK, Oct. 5, 2026 /PRNewswire/ -- Slang AI today announced a fundamental enhancement of its voice platform with the launch of the industry's first AI Superhost, purpose-built for full-service restaurants. The new release moves beyond traditional voice AI, which has historically been limited to scripted answers and basic reservation handling, and introduces a fully conversational, memory-aware, proactive hospitality agent that operates as a true extension of the restaurant team.

For full-service operators, the economics have never been more difficult. Margins are tight, labor is stretched, and guests now expect instant, personalized communication across phone, text, and web, twenty-four hours a day. Restaurants are losing revenue every shift to missed last-minute reservations, unanswered private dining inquiries, and slow back-and-forth on large party bookings. At the same time, staff bandwidth simply cannot keep up with the volume or the expectation of personal, emotionally intelligent hospitality at scale, and traditional voice AI hasn't been able to deliver it either. Plus, consumer expectations for technology, specifically AI, have never been higher. Guests want their reservations made and their questions answered on the first try, by a voice AI experience that actually understands tone and nuance.

Slang AI's new Superhost solves this end-to-end.

Here is what Superhost enables, with capabilities rolling out starting today and over the coming months:

- Emotionally intelligent conversation. Superhost can hear and understand the difference between an exasperated "ok" and a delighted "ok," and responds appropriately, so every guest feels genuinely heard and exceptionally cared for.

- Seamlessly handles interruptions. Guests can interrupt, change their minds mid-sentence, and have the kind of fluid back-and-forth they'd have with a seasoned host on the floor.

- 97 languages out of the box. Every restaurant, regardless of neighborhood or clientele, can serve guests in their preferred language.

- Sophisticated quality assurance. Unlike traditional voice AI, Superhost continuously monitors and reviews every call for quality, so hospitality teams don't have to. Paired with SOC 2 Type II attestation, it ensures enterprise-readiness. Superhost's voice AI guardrails are built by restaurants, so it stays on policy while handling any question.

- Guest memory. For the first time, the Superhost remembers prior conversations, preferences, and visit history. Regulars are recognized, upcoming reservations are known, allergies are recalled, and birthdays don't get forgotten.

- Enhanced OpenTable Experiences. Empower guests to inquire about and book OpenTable experiences. Superhost will respond with detailed, precise answers regarding the novel experience.

- Bespoke Personalities. Operators can tune accent, tone, and personality so the Superhost sounds like an authentic extension of their brand, whether that's a refined fine-dining concierge or a warm neighborhood trattoria host. Operators can even provide explicit instructions on specific language to avoid or lean into.

- Customizable Multilingual Greetings. Create custom greetings in 97 different languages.

- Unique Reservation Handling. Some restaurants have special reservations available for holidays like Valentine's Day and some allow large parties to be booked in a variety of ways. Custom reservation handling allows restaurants to capture all of those unique reservation cases.

- Custom Topics. Build custom topics specific to your restaurant. For example, if you have special themed events for every day of the week, you can create a topic to ensure Superhost mentions these to callers on the right day and time.

- Enhanced Intelligent Menu. Upload your menu to Slang to allow Superhost to field any and all questions a diner might have about your menu and ingredients.

"Restaurants don't need another voice bot. They need a teammate," said Alex Sambvani, CEO of Slang AI. "Operators are being asked to deliver world-class hospitality with thinner teams, more channels, and rising guest expectations. The Superhost is the first AI that actually shows up the way a great host does — remembering guests, anticipating needs, and following up afterward. It's not a tool. It's a member of the team."

Early customer results echo that. "Having worked in almost every facet of the hospitality business, I know just how important the guest experience is. It's everything. Superhost helps us scale exceptional service across locations by truly hearing and answering guests, which enables front-of-house staff to up the ante on their service," said Janet Zuccarini, Founder and CEO of Gusto54 Restaurant Group.

"I sit at the intersection of people and operations. The real challenge is scaling great hospitality, and that starts with giving your people the right tools. Slang does that for us. Superhost can answer questions, book reservations, and deliver the same panache as our best host," said Jason Berry, Co-Founder of KNEAD Hospitality + Design.

"Our entire mission is built around community, and that extends to our hospitality ethos. People are everything to us, and every touchpoint matters, not just on the floor, but on the phone, too. Superhost helps us deliver that same level of hospitality across every interaction," said Dan Simons, Co-Founder of Founding Farmers.

The new Slang AI Superhost is rolling out to full-service restaurant partners now. To learn more or request a demo, visit slang.ai.

Founded in 2019 by Alex Sambvani and Gabe Duncan, Slang AI is the first and leading AI platform purpose-built for the hospitality industry. Slang AI's Superhost answers every call with precision, warmth, and professionalism, booking reservations, handling inquiries, routing high-value requests, and recognizing returning guests, so restaurant staff can stay fully present with the guests in front of them. Serving thousands of restaurant locations globally with 95%+ guest satisfaction, Slang AI integrates with leading platforms including OpenTable, SevenRooms, Tripleseat, and Yelp. For more information, visit slang.ai.

SOURCE Slang AI

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SUGAR LAND, Texas, Oct. 5, 2026 /PRNewswire/ -- Applied Optoelectronics, Inc. (NASDAQ: AAOI) ("AOI"), a leading provider of advanced optical and HFC networking products that power AI, today announced that it has completed its previously disclosed $600 million "at-the-market" equity offering program (the "ATM Program").

AOI disclosed on August 21, 2026 that it filed a prospectus supplement with the U.S. Securities and Exchange Commission to offer and sell shares of its common stock having an aggregate offering price of up to $600,000,000. The Company sold a total of 5,694,845 shares at an average sales price of $105.36 per share, representing proceeds to the Company of $587,999,985.89, net of commissions and fees.

"We are pleased to have successfully completed our third at-the-market equity offering program this year, which strengthens our balance sheet and supports our ability to address growing demand for high-speed optical connectivity in AI data centers," said Dr. Thompson Lin, AOI's Founder, President and Chief Executive Officer. "We intend to use these proceeds to continue to make investments in the business, including new equipment and machinery for production and research and development use, as we continue to scale our advanced manufacturing capacity. We thank our shareholders for their continued support of AOI and welcome our new shareholders."

The Company currently intends to use the net proceeds from the ATM Program for general corporate purposes, which may include, among other things, debt repayment, working capital, and capital expenditures, primarily in support of its manufacturing expansion efforts for data center optical devices.

Forward-Looking Information

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. In some cases, you can identify forward-looking statements by terminology such as "believe," "may," "estimate," "continue," "anticipate," "intend," "should," "could," "would," "target," "seek," "aim," "predicts," "think," "objectives," "optimistic," "new," "goal," "priorities," "strategy," "potential," "is likely," "will," "expect," "momentum," "plan" "project," "permit," "positions" or by other similar expressions that convey uncertainty of future events or outcomes. These statements include management's beliefs and expectations regarding the use of proceeds from the ATM Program and planned investments in manufacturing capacity. Such forward-looking statements reflect the views of management at the time such statements are made. These forward-looking statements involve risks and uncertainties, as well as assumptions and current expectations, which could cause the company's actual results to differ materially from those anticipated in such forward-looking statements. These risks and uncertainties include but are not limited to: reduction in the size or quantity of customer orders; change in demand for the company's products due to industry conditions; changes in manufacturing operations; volatility in manufacturing costs; delays in shipments of products; disruptions in the supply chain; change in the rate of design wins or the rate of customer acceptance of new products; the company's reliance on a small number of customers for a substantial portion of its revenues; potential pricing pressure; a decline in demand for our customers' products or their rate of deployment of their products; general conditions in the internet datacenter, cable television (CATV) broadband, telecom, or fiber-to-the-home (FTTH) markets; changes in the world economy (particularly in the United States and China); changes in the regulation and taxation of international trade, including the imposition of tariffs; changes in currency exchange rates; the negative effects of seasonality; and other risks and uncertainties described more fully in the company's documents filed with or furnished to the Securities and Exchange Commission, including our Annual Report on Form 10-K for the year ended December 31, 2025 and our Quarterly report on Form 10-Q for the quarter ended June 30, 2026. More information about these and other risks that may impact the company's business are set forth in the "Risk Factors" section of the company's quarterly and annual reports on file with the Securities and Exchange Commission. You should not rely on forward-looking statements as predictions of future events. All forward-looking statements in this press release are based upon information available to us as of the date hereof, and qualified in their entirety by this cautionary statement. Except as required by law, we assume no obligation to update forward-looking statements for any reason after the date of this press release to conform these statements to actual results or to changes in the company's expectations.

About AOI  

Applied Optoelectronics, Inc. (AOI) is a leading developer and manufacturer of advanced optical and HFC networking products that are the building blocks for AI datacenters, CATV and broadband fiber access networks around the world. AOI supplies this critical infrastructure to tier-one customers across cloud computing, CATV broadband, telecom, and FTTH markets. The company has R&D facilities in Atlanta, GA, and engineering and manufacturing facilities at its corporate headquarters in Sugar Land, TX, as well as in Taipei, Taiwan and Ningbo, China. For additional information, visit www.ao-inc.com.  

SOURCE APPLIED OPTOELECTRONICS, INC.

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DaVinci Lock President Hayth to lead the executive team; Agnello joins from Go Store It; Oakley promoted to CTO as company builds its C-suite for an accelerated phase of growth

RALEIGH, N.C., Oct. 5, 2026 /PRNewswire/ -- 10 Federal, a leading technology-driven self-storage owner and operator, today announced the formation of a formal executive leadership team built to accelerate the company's growth. Geoff Hayth has been named President and Chief Customer Experience Officer (CXO), Beau Agnello has joined as Chief Operating Officer, and Brian Oakley has been promoted from Vice President of Technology to Chief Technology Officer, all effective September 28, 2026. Together with Chief A.I. Officer Christopher Taylor, appointed in April, the team reports to Co-CEOs Brad and Cliff Minsley.

10 Federal's record includes more than a decade of industry firsts, from pioneering the remote-managed facility model to building DaVinci Lock and Tenant Connect in-house to appointing the self-storage industry's first Chief A.I. Officer earlier this year. The formation of the executive leadership team is the first in a series of moves designed to significantly increase the company's rate of growth across acquisitions, third-party management and adjacent asset classes. Additional announcements are expected in the coming months.

Hayth joins the executive team from DaVinci Lock, the 10 Federal-founded access control platform he leads as President and will continue to lead. He previously spent eight years at Extra Space Storage, most recently as Director of Operations. Agnello joins from Go Store It Self Storage, where he served as Chief Operating Officer while the company grew from roughly 100 operating properties to more than 200 across 27 states, including its 2024 merger with Snapbox Self Storage that combined more than 10 million square feet under a single platform.

"Geoff has been part of 10 Federal's story for years, as a board member, as the leader who built DaVinci Lock into a platform used across the industry, and as one of the clearest thinkers we know on what customers actually want from a storage experience," said Brad Minsley, Co-CEO of 10 Federal. "The timing is intentional. We are entering a phase of tremendous growth, and we need the right people in the right seats ahead of what is to come. With Geoff, Beau, Brian and Chris in place, we have them. Cliff and I are taking a more active role in the company's day-to-day operations because we believe the next few years are the most important in this company's history, and we want to be on the field for them."

The appointments come during an active period of expansion. In recent months, 10 Federal opened two ground-up Class A facilities in Richmond Hill, Georgia, and Lake Worth, Texas, acquired three facilities in Azle and Springtown, Texas, adding more than 2,600 units and 375,000 net rentable square feet, and entered retail real estate with the acquisition of Eric Lane Shopping Center in Burlington, North Carolina.

Since acquiring its first self-storage facility in 2015, 10 Federal has built a proprietary automated management platform that includes predictive analytics, automated access control, A.I.-driven property auditing, drone-based security and A.I.-powered voice and customer service agents. That platform now supports operations at 131 properties across 15 states. The executive team's mandate is to extend it across a much larger footprint.

Geoff Hayth, President and Chief Customer Experience Officer

Hayth has served as President of DaVinci Lock since 2022, leading the development of its customer-facing platform and its growth into an access control system now used in 1 out of every 6 storage facilities nationwide. He has also served as a board member and strategic advisor across the 10 Federal family of companies. As President and Chief Customer Experience Officer, Hayth will lead the executive team and own the customer experience across 10 Federal's platform as the company grows.

"We built an industry leading operating platform, and we are primed and ready to grow quickly as we enter this next phase," said Hayth. "I worked alongside Beau at Extra Space, and I know exactly how capable he is as both an operator and a leader. He isn't joining 10 Federal to maintain what we've built. He's joining to multiply it. Pairing him with Brian, who built the technology foundation this company runs on, and Chris, who is building what comes next, gives us a leadership team that can carry this platform a long way."

Beau Agnello, Chief Operating Officer

Agnello brings more than 14 years of self-storage operating experience across public REIT, private equity-backed and owner-operator platforms. He began his career at Extra Space Storage in 2012 and rose to Division Vice President, overseeing approximately 170 properties and 11 million square feet across Texas and Oklahoma. He later led operations for a privately held owner-operator before joining Go Store It as Chief Operating Officer in 2023, where he led the integration of the Snapbox merger and the company's investments in remote operations and contact center performance. As Chief Operating Officer, he will oversee operations and marketing for 10 Federal's automated self-storage portfolio and growing third-party management business, including field and remote operations, revenue management and the onboarding of newly acquired and managed properties.

"Most operators say their people are the key to their success, but very few use technology to actually put their best people in front of the customer every time," said Agnello. "10 Federal is the exception. The automation here isn't a pilot program, it's business. My job is to take that platform and scale it, and I don't think there is a better place in self-storage to do that right now."

Brian Oakley, Chief Technology Officer

Oakley has led 10 Federal's technology organization since joining the company in 2023, directing the enterprise platforms, automation and digital infrastructure that underpin its remote-managed operating model. He previously served as Vice President of Technology at Realterm, an independent global investment manager focused on transportation real estate, where he led enterprise technology strategy and a firm-wide digital transformation as assets under management grew from approximately $1 billion to $12 billion. Earlier, he held technology, data architecture and quantitative roles at T. Rowe Price and the Johns Hopkins University Applied Physics Laboratory. As Chief Technology Officer, Oakley will oversee technology strategy, product and enterprise platforms across the company, working alongside Taylor to bring A.I. capabilities into production at scale.

"Every product and platform decision we make gets measured against three things: does it improve the customer experience, does it make the operation more efficient, and does it create greater value for our investors?" said Oakley. "We believe the best technology should accomplish all three. My job as CTO is to make sure that remains true as we grow."

Media Contact: Geoff Hayth, President and CXO, [email protected]

About 10 Federal

10 Federal is a leading innovator in the self-storage industry, with 131 managed properties across 15 states. As one of the largest owners and operators of fully automated self-storage facilities in the country, the company harnesses advanced technology, artificial intelligence, and data analytics to deliver superior risk-adjusted returns. Recognized as an Inc. 5000 Fastest Growing Company in America, an Inside Self-Storage (ISS) Top 100 Operator, a Top Performing Real Estate Fund by Preqin, and a Top Fundraiser by Juniper Square, 10 Federal has built an automated management platform that redefines operational efficiency in the modern self-storage industry. For more information, visit www.10fed.com.

SOURCE 10 Federal

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New research shows that a non-invasive urine sample can reveal not just whether a tumor is present, but how it will respond to treatment, expanding what cell-free RNA diagnostics can do beyond detection alone.

SAN CARLOS, Calif., Oct. 5, 2026 /PRNewswire/ -- Resero Bio, a precision diagnostics company building a cell-free RNA (cfRNA) liquid biopsy platform, today announced publication of a Stanford-led study in Nature Medicine demonstrating that analysis of urine cfRNA can detect bladder cancer non-invasively and identify molecular residual disease (MRD). It also showed the ability to distinguish tumor aggressiveness and predict which patients will respond to immunotherapy versus chemotherapy. The publication marks a key milestone for Resero Bio, providing clinical validation for the RARE-seq platform the company is building out across both urine and plasma, and across multiple cancer types.

"This study presents the clearest evidence yet that cell-free RNA carries far more clinically relevant information than a binary detection call," said Monica Nesselbush, PhD, CEO and Co-founder of Resero Bio. "We're not just asking whether cancer is present. We're reading out gene expression programs associated with tumor grade, stage, immune biology, and treatment response, all from a urine sample. Moving beyond detection to deeper characterization is the foundation of our platform, and bladder cancer represents a prime example of how that capability can deliver value throughout the patient journey."

Researchers from Stanford Cancer Institute, the VA Palo Alto Health Care System, and collaborating institutions analyzed 683 urine samples from bladder cancer patients and controls using uRARE-seq, a proprietary targeted cfRNA sequencing method for urine samples built on Resero Bio's core RARE-seq technology. Building on previously presented work showing that urine cfRNA analysis enables detection of localized bladder cancer with high sensitivity and specificity, the new publication reports findings that move the platform beyond detection and into the realm of tumor biology. Highlights of the study are provided below.

The cfRNA liquid biopsy platform enabled:

- Highly sensitive detection of bladder cancer from pre-treatment urine along with discrimination of low-grade from high-grade bladder tumors and non-muscle invasive from muscle-invasive disease — two determinations that currently require tissue sampling via biopsy or resection.

- Identification of a pre-treatment molecular signature of immunotherapy response. Patients who achieved a complete molecular response to BCG immunotherapy showed pre-existing anti-tumor immune response signatures in urine cfRNA before treatment even began.

- Identification of MRD after treatment, distinguishing patients with complete molecular responses to surgery from those with incomplete responses to surgery who then responded to adjuvant BCG. Patients with complete molecular responses to either surgery or BCG showed much lower risk for recurrence than those with detectable tumor cfRNA after treatment.

- Detection of transcriptionally distinct cfRNA profiles in urine samples from patients with renal cell carcinoma and prostate adenocarcinoma, providing preliminary evidence that urine cfRNA can be used for kidney and prostate cancer applications as well.

"Bladder cancer management is full of moments where a clinician has to make a consequential decision with incomplete information: How aggressive is this tumor? Will it respond to BCG? Is there residual disease after treatment?" said Max Diehn, MD, PhD, Co-founder and Scientific Advisor of Resero Bio. "Liquid biopsies have mostly been used to detect the presence of cancer. This work shows they can also help inform treatment strategy, which is ultimately what matters most to providers and their patients."

Ash Alizadeh, MD, PhD, Co-founder and Scientific Advisor of Resero Bio, said, "What's compelling about this dataset is that the biology holds up across independent training and validation cohorts, and the predictive signal for BCG response was there before treatment even started. That kind of pre-treatment stratification is exactly what's needed to make smarter, faster decisions in the clinic and in the drug development pipelines built around these patients."

While this publication centers on bladder cancer and urine, the RARE-seq platform is disease- and biofluid-agnostic by design. With capture panels optimized for both urine and plasma, proof-of-concept cfRNA signal has been generated at Resero Bio and Stanford across ten solid tumor types to date. Resero Bio's platform is available now for research use.

About Resero Bio

Resero Bio is a precision diagnostics company unlocking the full potential of precision medicine by measuring the cell-free transcriptome. Its proprietary liquid biopsy platform, RARE-seq, is purpose built for cell-free RNA sequencing with an AI/ML-enabled bioinformatics engine to deliver biologically meaningful, clinically actionable insights from plasma or urine — without requiring tissue or prior tumor sequencing. The platform supports non-invasive cancer detection, molecular and histological subtyping, risk stratification, treatment response prediction, pharmacodynamic monitoring, toxicity assessment, and characterization of resistance mechanisms across cancer types. Founded by researchers from Stanford Medicine, Resero Bio is based in San Carlos, California, and is exclusively licensed to develop the RARE-seq platform for commercial use. For more information, visit reserobio.com.

Media Contact

Monica Nesselbush

[email protected]

SOURCE Resero Bio

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—Sara Bonstein Will Step Down as CFO on October 30 After Nearly Seven Years of Dedicated Leadership—

—Company Reaffirms Full-Year 2026 Financial Guidance—

—Company Announces Third-Quarter 2026 Financial Results Conference Call to Be Held on Thursday, October 29, 2026—

BRIDGEWATER, N.J., Oct. 5, 2026 /PRNewswire/ -- Insmed Incorporated (Nasdaq: INSM), a people-first global biopharmaceutical company striving to deliver first- and best-in-class therapies to transform the lives of patients facing serious diseases, today announced that Sara Bonstein will step down as Chief Financial Officer (CFO). Ms. Bonstein will continue to serve as CFO until October 30, 2026, to ensure a smooth transition through the Company's reporting of its third-quarter 2026 financial results and she will participate in the earnings call on Thursday, October 29, 2026. Insmed has commenced a search to identify the Company's next CFO.

"We are grateful for Sara's many contributions over the past almost seven years and her dedicated leadership overseeing our finance organization during a time when Insmed raised more than $4.2 billion in capital," said Will Lewis, Chair and Chief Executive Officer of Insmed. "We are now well positioned to reach cash flow positivity next year with what we view as a clear path toward sustained top-line growth and bottom-line profitability."

"Serving as Insmed's CFO has been a privilege of my career," said Ms. Bonstein. "I am thankful for our team and all we achieved together during my time with the Company. I am confident in Insmed's future, especially given our successful launch of BRINSUPRI coupled with our exciting pipeline. After considerable reflection, now is an ideal time for me to pursue my ambition for a broader leadership role."

Lewis continued, "Sara has been a steadfast partner in building Insmed into the company we are today, and we wish her well as she pursues her next leadership opportunity. Insmed has undergone a major transformation in recent years to become a global diversified biotech company with a robust portfolio of first- or best-in-class therapies with the potential to deliver meaningful impact for patients with serious diseases. With BRINSUPRI and ARIKAYCE on track to deliver meaningful revenue this year, and with substantial growth expected in the years ahead through our commercial portfolio and diverse therapeutic pipeline, we remain focused on delivering on our long-term ambitions. We are committed to ensuring our finance operations continue supporting Insmed's success in our next phase of growth, and we have partnered with a leading executive search firm to identify our next CFO."

Ms. Bonstein's transition is not related to any disagreement between Ms. Bonstein and the Company on any matter relating to the Company's accounting practices, financial statements, internal controls, or operations.

Reaffirms Full-Year 2026 Guidance

As Insmed continues to build on its operational excellence and momentum, the Company reaffirms its full-year 2026 financial guidance of revenue in the range of $1.25 billion to $1.40 billion for BRINSUPRI® (brensocatib) and $450 million to $470 million for ARIKAYCE® (amikacin liposome inhalation suspension).

Third-Quarter 2026 Earnings Conference Call

Insmed announced today that it will release its third-quarter 2026 financial results on Thursday, October 29, 2026.

Insmed management will host a conference call for investors beginning at 8:00 a.m. ET on Thursday, October 29, 2026, to discuss financial results and provide a business update.

Shareholders and other interested parties may participate in the conference call by dialing (833) 461-5787 (U.S.) and (585) 542-9983 (international) and referencing access code 603611044. The call will also be webcast live on the Company's website at www.insmed.com.

A replay of the conference call will be accessible approximately 2 hours after its completion through November 5, 2026, by dialing (833) 309-1852 (U.S.) and (929) 828-5978 (international) and referencing access code 603611044. A webcast of the call will also be archived for 90 days under the Investor Relations section of the Company's website at www.insmed.com.

About ARIKAYCE

ARIKAYCE® is approved in the United States as ARIKAYCE (amikacin liposome inhalation suspension), in Europe as ARIKAYCE Liposomal 590 mg Nebuliser Dispersion, and in Japan as ARIKAYCE inhalation 590 mg (amikacin sulfate inhalation drug product). Current international treatment guidelines recommend the use of ARIKAYCE for appropriate patients. ARIKAYCE is a novel, inhaled, once-daily formulation of amikacin, an established antibiotic that was historically administered intravenously and associated with severe toxicity to hearing, balance, and kidney function. Insmed's proprietary PULMOVANCE™ liposomal technology enables the delivery of amikacin directly to the lungs, where liposomal amikacin is taken up by lung macrophages where the infection resides, while limiting systemic exposure. ARIKAYCE is administered once daily using the Lamira® Nebulizer System manufactured by PARI Pharma GmbH (PARI).

About PARI Pharma and the Lamira® Nebulizer System

ARIKAYCE is delivered by a novel inhalation device, the Lamira® Nebulizer System, developed by PARI. Lamira® is a quiet, portable nebulizer that enables efficient aerosolization of ARIKAYCE via a vibrating, perforated membrane. Based on PARI's 100-year history working with aerosols, PARI is dedicated to advancing inhalation therapies by developing innovative delivery platforms to improve patient care.

BOXED WARNING AND IMPORTANT SAFETY INFORMATION FOR ARIKAYCE IN THE U.S.

Hypersensitivity Pneumonitis has been reported with the use of ARIKAYCE in the clinical trials. Hypersensitivity pneumonitis (reported as allergic alveolitis, pneumonitis, interstitial lung disease, allergic reaction to ARIKAYCE) was reported at a higher frequency in patients treated with ARIKAYCE plus background regimen (3.1%) compared to patients treated with a background regimen alone (0%). Most patients with hypersensitivity pneumonitis discontinued treatment with ARIKAYCE and received treatment with corticosteroids. If hypersensitivity pneumonitis occurs, discontinue ARIKAYCE and manage patients as medically appropriate.

Hemoptysis has been reported with the use of ARIKAYCE in the clinical trials. Hemoptysis was reported at a higher frequency in patients treated with ARIKAYCE plus background regimen (17.9%) compared to patients treated with a background regimen alone (12.5%). If hemoptysis occurs, manage patients as medically appropriate.

Bronchospasm has been reported with the use of ARIKAYCE in the clinical trials. Bronchospasm (reported as asthma, bronchial hyperreactivity, bronchospasm, dyspnea, dyspnea exertional, prolonged expiration, throat tightness, wheezing) was reported at a higher frequency in patients treated with ARIKAYCE plus background regimen (28.7%) compared to patients treated with a background regimen alone (10.7%). If bronchospasm occurs during the use of ARIKAYCE, treat patients as medically appropriate.

Exacerbations of underlying pulmonary disease has been reported with the use of ARIKAYCE in the clinical trials. Exacerbations of underlying pulmonary disease (reported as chronic obstructive pulmonary disease (COPD), infective exacerbation of COPD, infective exacerbation of bronchiectasis) have been reported at a higher frequency in patients treated with ARIKAYCE plus background regimen (14.8%) compared to patients treated with background regimen alone (9.8%). If exacerbations of underlying pulmonary disease occur during the use of ARIKAYCE, treat patients as medically appropriate.

Anaphylaxis and Hypersensitivity Reactions: Serious and potentially life-threatening hypersensitivity reactions, including anaphylaxis, have been reported in patients taking ARIKAYCE. Signs and symptoms include acute onset of skin and mucosal tissue hypersensitivity reactions (hives, itching, flushing, swollen lips/tongue/uvula), respiratory difficulty (shortness of breath, wheezing, stridor, cough), gastrointestinal symptoms (nausea, vomiting, diarrhea, crampy abdominal pain), and cardiovascular signs and symptoms of anaphylaxis (tachycardia, low blood pressure, syncope, incontinence, dizziness). Before therapy with ARIKAYCE is instituted, evaluate for previous hypersensitivity reactions to aminoglycosides. If anaphylaxis or a hypersensitivity reaction occurs, discontinue ARIKAYCE and institute appropriate supportive measures.

Ototoxicity has been reported with the use of ARIKAYCE in the clinical trials. Ototoxicity (including deafness, dizziness, presyncope, tinnitus, and vertigo) were reported with a higher frequency in patients treated with ARIKAYCE plus background regimen (17%) compared to patients treated with background regimen alone (9.8%). This was primarily driven by tinnitus (7.6% in ARIKAYCE plus background regimen vs 0.9% in the background regimen alone arm) and dizziness (6.3% in ARIKAYCE plus background regimen vs 2.7% in the background regimen alone arm). Closely monitor patients with known or suspected auditory or vestibular dysfunction during treatment with ARIKAYCE. If ototoxicity occurs, manage patients as medically appropriate, including potentially discontinuing ARIKAYCE.

Nephrotoxicity was observed during the clinical trials of ARIKAYCE in patients with MAC lung disease but not at a higher frequency than background regimen alone. Nephrotoxicity has been associated with the aminoglycosides. Close monitoring of patients with known or suspected renal dysfunction may be needed when prescribing ARIKAYCE.

Neuromuscular Blockade: Patients with neuromuscular disorders were not enrolled in ARIKAYCE clinical trials. Patients with known or suspected neuromuscular disorders, such as myasthenia gravis, should be closely monitored since aminoglycosides may aggravate muscle weakness by blocking the release of acetylcholine at neuromuscular junctions.

Retired Army veteran opens Caring Senior Service in Fort Worth

New owner brings a career of service to seniors and the military community

FORT WORTH, Texas, Oct. 5, 2026 /PRNewswire/ -- Caring Senior Service, a non-medical, personalized home care services company, has opened a new Fort Worth-area location led by retired Army veteran Marquita Foxworth.

Foxworth's interest in senior care grew through her work with fellow veterans. Through a veterans group she helped establish three years ago, she regularly visited hospitals and rehabilitation centers, where she saw families suddenly taking on major caregiving responsibilities for aging loved ones.

"Serving in the Army taught me that people do better when they know someone is in their corner," Foxworth said. "I've seen families step up for the people they love, but they shouldn't have to figure everything out on their own. I want this business to be one more place they can turn for help."

The new office, located at 550 East Bailey Boswell Road, Building 3, Suite 320A, in Saginaw, will provide personalized in-home care services to seniors throughout the Fort Worth area.

"Marquita brings a strong sense of leadership and purpose to this new location," said Jeff Salter, CEO and founder of Caring Senior Service. "She's thoughtful about the kind of business she wants to build and the role she wants it to play in the Fort Worth community."

For Foxworth, who was born and raised in Beaumont, Texas, opening Caring Senior Service is also a continuation of the service-oriented path she has followed throughout her career. She hopes to build a business that supports older adults, serves local families and remains connected to the veteran community.

"I want to leave behind something that reflects the way I've tried to live my life," Foxworth said. ""For me, that means showing up for people when they need support and giving families someone they can count on."

For more information about Caring Senior Service in Fort Worth, please visit https://caringseniorservice.com/fort-worth/ or call 817-765-6375.

About Caring Senior Service

Caring Senior Service is a non-medical home care services company based in San Antonio, Texas. Founded by CEO Jeff Salter in 1991, the company provides assistance to seniors, people with disabilities, and any adult who may need help with the tasks of everyday living, such as bathing, personal care, running errands, and preparing food. After adding locations throughout Texas in the 1990s, the company extended its reach through franchising in 2002. It now boasts more than 60 locations throughout the United States.

For more information on Caring Senior Service, please visit caringseniorservice.com.

SOURCE Caring Senior Service

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More Than Five Decades In, Botanical Wellness Leader Marks Next Chapter of Growth with First Tea Produced on the East Coast

ROCKY MOUNT, Va., Oct. 5, 2026 /PRNewswire/ -- Traditional Medicinals, a leader in botanical wellness for over 50 years, today announced that its new $47 million, 110,000-square-foot manufacturing facility in Franklin County, VA, has officially commenced tea production, marking a major growth milestone and the start of a long-term Traditional Medicinals presence in Virginia. The facility, located in Summit View Business Park, is the company's second manufacturing site, joining its original facility in Sebastopol, CA. The expansion marks the company's move to bicoastal manufacturing, a shift that supports more efficient, sustainable distribution and positions Traditional Medicinals to meet growing consumer demand for botanical wellness products nationwide.

Traditional Medicinals built the new facility on the skills and trades already in Franklin County, a choice that reflects the company's deep investment in the community. All major design and construction partners were regionally based, including MB Contractors, Interactive Design Group, ProCon Inc., Jamison Electric, Varney Inc., and Bowman Excavation, and the facility is the first and only tilt-up concrete construction project in Franklin County. Traditional Medicinals applied the same local-first approach to hiring, staffing the facility's startup entirely with locally hired talent, creating 19 new jobs in Franklin County to date. In keeping with Traditional Medicinals' commitment to sustainable growth, the all-electric facility uses no on-site fossil fuels, and its four bioswales capture and naturally filter 100% of runoff from the roof and parking areas.

"This is a proud moment for our team and for Franklin County," said Joe Stanziano, CEO of Traditional Medicinals. "We didn't just build a facility here — we built relationships, hired locally, and listened to this community every step of the way. This is just the start of what we hope will be a long and mutually rewarding partnership with Virginia."

The first product run at the new facility is for Throat Coat® Tea, one of Traditional Medicinals' best-selling products, chosen in part for its local significance: one of its key ingredients, slippery elm, is sourced domestically throughout Appalachia. Traditional Medicinals also supports ongoing research into the slippery elm tree through a partnership with Virginia Tech — another example of the deep community roots the company is building in the area.

The Sebastopol facility will continue operating at full capacity, producing Traditional Medicinals' full line of more than 60 herbal teas, while Virginia ramps up to produce the same. The Virginia facility's proximity to East Coast transportation networks will support the company's ethical sourcing relationships with herb suppliers in over 35 countries while improving distribution efficiency to the East Coast.

Since breaking ground in July 2025, Traditional Medicinals has worked to build lasting ties with the community, including the Virginia Economic Development Partnership, Franklin County, Roanoke Regional Partnership, Friends of Ferrum Park, Appalachian Sustainable Development, Appalachian Harvest Herb Hub, and Virginia Tech. The project is expected to generate over $62 million in economic impact for the region.

"Since we broke ground, it's been remarkable to watch this site go from an empty field to a working facility, together with this community," said Steve Bess, plant director of Traditional Medicinals' Virginia facility. "None of it would have happened without Rocky Mount and Franklin County's support and collaboration, and we're proud to call this community home."

Traditional Medicinals was founded in 1974 on the belief that plants have the power to heal both people and the planet, an ethos that has guided the company for more than 50 years. That commitment to purpose-driven growth carried through to the Virginia project itself, from building greenfield rather than retrofitting an existing site, to staffing the new facility with local talent. As Traditional Medicinals enters this next chapter, its commitment to growing with purpose and intention remains unchanged, with a continued focus on sourcing responsibly, investing in the communities where it operates, and staying true to the values that have built the business for five decades.

About Traditional Medicinals

Traditional Medicinals is the leader in botanical wellness with a purpose to inspire active connection to plant wisdom in service of people and planet. Founded in 1974, Traditional Medicinals is rooted in herbal medicine that includes ethical sourcing and production, and rigorous attention to purity, quality, and sustainability standards. With more than 60 teas, lozenges, and capsules expertly formulated by herbalists, Traditional Medicinals has a deep commitment to both scientific rigor and traditional plant knowledge. Certified as Fair for Life®, Certified B Corporation, California Benefit Corporation, and California Green Business, Traditional Medicinals commits to elevating communities across the globe, helping ecosystems thrive, and fortifying cultural connections. In 2026, Traditional Medicinals earned its spot on the Inc. 5000 list, the company's first appearance on the annual ranking of America's fastest-growing private companies. Traditional Medicinals products are available online, and in most grocery and natural foods retailers. For additional information, visit www.traditionalmedicinals.com.

SOURCE Traditional Medicinals

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DUBLIN, Oct. 5, 2026 /PRNewswire/ -- AerCap Holdings N.V. ("AerCap") (NYSE: AER) has announced its major business transactions during the third quarter 2026:

- Signed 85 lease agreements, including 16 widebody aircraft, 45 narrowbody aircraft, 13 engines and 11 helicopters.

- Completed 34 purchases of 32 aircraft (including 8 Airbus A320neo Family aircraft, 20 Boeing 737 MAX aircraft, 2 Boeing 787-9s and 2 Embraer E195-E2s for AerCap's owned portfolio) and 2 helicopters.

- Completed 85 sale transactions for 65 aircraft (including 15 Airbus A320 Family aircraft, 4 Airbus A320neo Family aircraft, 1 Airbus A321 Freighter aircraft, 3 Airbus A330s, 3 Airbus A350s, 7 Boeing 737NGs, 2 Boeing 737 MAX aircraft, 9 Boeing 767 Freighter aircraft, 2 Boeing 777-200ERs, 4 Embraer E190s and 2 Embraer E195-E2s from AerCap's owned portfolio and 13 aircraft from AerCap's managed portfolio), 13 engines (including 11 engines from AerCap's owned portfolio and 2 engines from AerCap's managed portfolio) and 7 helicopters.

- Signed financing transactions for approximately $900 million.

- Repurchased 5.3 million shares, at an average price of $147.12 per share, for a total of approximately $783 million.

- Declared quarterly cash dividend on ordinary shares of $0.40 per share.

About AerCap

AerCap is the global leader in aviation leasing with one of the most attractive order books in the industry. AerCap serves approximately 300 customers around the world with comprehensive fleet solutions. AerCap is listed on the New York Stock Exchange (AER) and is headquartered in Dublin with offices in Miami, Shannon, Memphis, Singapore, London, Dubai, Shanghai, Amsterdam and other locations around the world.

Forward-Looking Statements

This press release contains certain statements, estimates and forecasts with respect to future performance and events. These statements, estimates and forecasts are "forward-looking statements". In some cases, forward-looking statements can be identified by the use of forward-looking terminology such as "may," "might," "should," "expect," "plan," "intend," "will," "aim," "estimate," "anticipate," "believe," "predict," "potential" or "continue" or the negatives thereof or variations thereon or similar terminology. All statements other than statements of historical fact included in this press release are forward-looking statements and are based on various underlying assumptions and expectations and are subject to known and unknown risks, uncertainties and assumptions, and may include projections of our future financial performance based on our growth strategies and anticipated trends in our business. These statements are only predictions based on our current expectations and projections about future events. There are important factors that could cause our actual results, level of activity, performance or achievements to differ materially from the results, level of activity, performance or achievements expressed or implied in the forward-looking statements, including but not limited to the availability of capital to us and to our customers and changes in interest rates; the ability of our lessees and potential lessees to make lease payments to us; our ability to successfully negotiate flight equipment (which includes aircraft, engines and helicopters) purchases, sales and leases, to collect outstanding amounts due and to repossess flight equipment under defaulted leases, and to control costs and expenses; changes in the overall demand for commercial aviation leasing and aviation asset management services; the impact of the conflict in the Middle East, including the Iran conflict, or any escalation thereof, on the aviation industry or our business; the continued impacts of the Ukraine Conflict, including the resulting sanctions by the United States, the European Union, the United Kingdom and other countries, on our business and results of operations, financial condition and cash flows; the effects of terrorist attacks on the aviation industry and on our operations; the economic condition of the global airline and cargo industry and economic and political conditions; trade tensions, including actual or threatened U.S. tariffs and retaliatory measures by some countries, and the resulting geopolitical uncertainty; development of increased government regulation, including travel restrictions, sanctions, regulation of trade and the imposition of import and export controls, tariffs and other trade barriers; a downgrade in any of our credit ratings; competitive pressures within the industry; regulatory changes affecting commercial flight equipment operators, flight equipment maintenance, engine standards, accounting standards and taxes; and disruptions and security breaches affecting our information systems or the information systems of our third-party providers.

As a result, we cannot assure you that the forward-looking statements included in this press release will prove to be accurate or correct. These and other important factors and risks are discussed in AerCap's annual report on Form 20-F and other filings with the United States Securities and Exchange Commission. In light of these risks, uncertainties and assumptions, the future performance or events described in the forward-looking statements in this press release might not occur. Accordingly, you should not rely upon forward-looking statements as a prediction of actual results and we do not assume any responsibility for the accuracy or completeness of any of these forward-looking statements. Except as required by applicable law, we do not undertake any obligation to, and will not, update any forward-looking statements, whether as a result of new information, future events or otherwise.

For more information regarding AerCap and to be added to our email distribution list, please visit www.aercap.com.

SOURCE AerCap Holdings N.V.

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Media Consulting Group (MCG) becomes the technology layer that optimizes Diray Media's streaming supply before a single bid is placed — extending a media company built on measurable outcomes, upstream.

NEW YORK, Oct. 5, 2026 /PRNewswire/ -- Diray Media, the woman-owned, WBENC-certified performance media company pairing four decades of media expertise with its own proprietary optimization technology, has selected Media Consulting Group (MCG) as its upstream optimization partner for streaming TV. Recognizing that the supply side was the next frontier in its performance discipline, Diray identified MCG's buy-side-focused optimization as the missing layer — one that structures and continuously improves the streaming supply behind Diray's campaigns before it ever reaches the bid.

Diray has built its reputation on turning media into measurable business impact— by scoring every placement against client outcomes and adjusting until performance improves. Diray identified the supply side as the next lever in that discipline and chose MCG to shape supply procurement upstream, before a placement is ever won. MCG's distinct approach to securing streaming inventory starts with Diray's sophisticated buying practices, using those insights to shape higher-quality, more relevant supply before it reaches the bid. The two functions were built to work together: Diray's technology proves out what happens after the buy; MCG's optimization shapes what is available to buy in the first place.

What the partnership delivers for Diray Media's clients. Diray now pairs its optimization technology with an upstream supply layer of its own choosing: MCG continuously analyzes and shapes the supply behind Diray's campaigns — reducing exposure to low-value or over-concentrated inventory before it reaches the DSP and expanding reach on the sources that perform. As a single, neutral, buy-side-only layer across the major supply platforms Diray runs on.. The result, as Diray designed it, is a cleaner operational layer: ready-to-activate deal IDs for the DSPs Diray already uses, ongoing visibility and control at the supply level, and more room for Diray's strategists and buyers to stay focused on client outcomes.

From the partners

ABOUT MEDIA CONSULTING GROUP

Media Consulting Group (MCG) is a buy-side-focused media consulting and activation partner. Working upstream on the supply side through optimization, insights, and analysis, MCG improves how supply is structured and activated before it reaches the bidder, helping agencies, brands, and traders get more out of their media spend. MCG only generates revenue when it creates measurable value. Learn more at wermcg.com.

ABOUT DIRAY MEDIA

Diray Media is a woman-owned, WBENC-certified performance media company pairing four decades of hands-on media expertise with its own proprietary optimization technology. Diray's strategists, buyers, and analysts work directly on every account, turning what a campaign produces into the outcomes that matter most to each client: sales, orders, leads, and market share. Learn more at diraymedia.com.

SOURCE Media Consulting Group

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